The leading causes of cTnI increase in these patients were heart failure (21.8%), respiratory disorders (16.9%), AMI (7.3%), tachyarrhythmia (6.5%), digestive disorders (4.8%), neurological diseases (4.7%), CRF (3.0%), infectious diseases (2.6%) and pulmonary embolism (1.9%). Here, TNNI3 is linked to nervous system disorder.