Both HLA-B*07:05 and HLA-C*15:05 alleles are absent from the 2752 NPC cases, but only present in ~1% control population (n = 2937) (HLA-B*07:05, OR < 0.015, P = 5.83 × 10−21 and HLA-C*15:05, OR < 0.017, P = 5.19 ×10 −18). The gene discussed is HLA-B; the disease is nasopharyngeal carcinoma.