Among the 190 HLA class I alleles, we confirmed NPC risk association for seven common HLA-A/B/C alleles (HLA-A*11:01, HLA-A*02:07, HLA-B*46:01, HLA-B*55:02, HLA-B*13:01, HLA-C*01:02, and HLA-C*03:04, Supplementary Table 3). Here, HLA-A is linked to nasopharyngeal carcinoma.