SERPINE1 and esophageal squamous cell carcinoma: A previous study reported that macrophages expressed LRP1 [37], and in the present study, we confirmed that CD204+ macrophages in human ESCC tissue, TAMs, expressed LRP1 by double immunofluorescence (Fig. 6e), and that the expression level of PAI-1 in stromal cells was associated with high numbers of infiltrating CD204+ macrophages.