Two CRF novel loci, ATP1B1-LINC00970 (locus 5) and SLC25A22 (locus 78), together with the previously reported TCF4 (locus 126), map to FECD risk loci24, with close match of association plots (Supplementary Fig. 2). Here, ATP1B1 is linked to Fuchs endothelial corneal dystrophy.