All have been previously prioritized in relation to CCT7,8 or keratoconus11, apart from rs77583146, p.Gly165Arg in WNT10A. This latter is 146 bp away from another low-frequency missense variant, rs121908120, reported for CCT and keratoconus risk22, identified here as an independent functional variant candidate. This evidence concerns the gene CCT7 and keratoconus.