TP53 and Merkel cell skin cancer: Gene set enrichment analysis (GSEA) of the scRNAseq data for a primary MCC described above (Fig. 1b; Supplementary Fig. S2c) comparing the CAFhigh and CAFlow fibroblast clusters based on the established CAF score demonstrated that the p53-related pathway is more strongly inhibited in CAFhigh fibroblasts than in CAFlow fibroblasts (Fig. 7g).