To investigate the expression level of SORBS2 in ccRCC, 37 primary tissues, 56 metastatic tissues (including 17 lymph node metastases, 13 liver metastases, 23 lung metastases, and 6 bone metastases), and their corresponding adjacent normal tissues were detected by qRT-PCR. The gene discussed is SORBS2; the disease is nonpapillary renal cell carcinoma.