Typically, bvFTD presents in the sixth decade of life, but in patients with FUS pathology onset is considerably younger, often in the fourth decade.13 Other pathologies are also possible in younger patients though.14 Hyperorality and dietary change in bvFTD are associated with both FUS and tau pathologies, but typically not TDP-43.15 This evidence concerns the gene TARDBP and behavioral variant of frontotemporal dementia.