However, the association between TROP2 and KI-67 was greatest in Hp+/KRAS+ mice at 12 wk, where a median of 86% of TROP2+ glands or gland fragments were KI-67+ (P < 0.01) (Fig 7C), suggesting that Hp infection increases the proliferation of dysplastic glands. Here, MKI67 is linked to infection.