There was also an increased relative mRNA expression of c-Myc, GLS1, ASCT2, and SN2 in CD138+ malignant plasma cells compared to their paired CD138- mononuclear cells in MM patients supporting the previous observation of a higher mean 13C labeling of the TCA cycle intermediates (glutamate, citrate, fumarate, malate, and aspartate) in CD138+ malignant plasma cells from MM patients compared to their paired CD138- mononuclear cells. The gene discussed is MYC; the disease is Miyoshi myopathy.