For instance, we detected a syncytiotrophoblast-specific association between IQ and ATP2B1, a gene that has been implicated in preeclampsia [66, 67], an in utero condition that is partially mediated by dysfunctional syncytiotrophoblasts [99] and has negative impacts with childhood neurodevelopment [100, 101]. The gene discussed is ATP2B1; the disease is preeclampsia.