SMARCA2 and orofaciodigital syndrome I: For example, SMARCA2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 2) and DDX59 has been implicated in development disorders of the brain, such as Nicolaides-Baraitser syndrome and epilepsy, and other developmental disorders, such as dysfunctional central nervous system development and orofaciodigital syndrome [68–73].