MTOR and autosomal dominant polycystic kidney disease: They reported that the NPS-R568 (an activator of calcium channel receptor) in a conditionally immortalized proximal tubular epithelial cells (ciPTEC) derived from a patient with ADPKD showed an increased calcium level and reduced activity of cAMP and mammalian target of rapamycin (mTOR) as compared to its wild type (wt) clone; ciPTECwt, that indicated the potential role of intracellular calcium in ADPKD (Mise et al. 2018).