This is the most frequently discussed mechanism for how viruses or bacteria could induce autoimmunity in MS, that occurs when peptides from pathogens (antigens) share sequence or structural homology with host peptides (self-antigens), in the case of MS with CNS antigens (e.g. Myelin Basic Protein, Myelin oligodendrocyte glycoprotein) [35]. This evidence concerns the gene MBP and myeloid sarcoma.