After adjusting for confounding factors like demographic data (age, sex, and body mass index), dialysis information (interdialytic weight gain, residual renal function, dialysis vintage and single-pool Kt/V), comorbid conditions (history of primary hypertension, coronary heart disease, and diabetes), biochemical data (serum albumin, pre-albumin, creatinine and hemoglobin), cardiac conditions (NT- proBNP, LV mass index, LVEF, and left atrium diameter index), and predialysis BP (predialysis systolic BP and diastolic BP), UFR was still a predictor for IDH (p < .05) (Table 2). This evidence concerns the gene NPPB and diabetes mellitus.