TBX5 and coronary artery disorder: In the current investigation, a novel heterozygous TBX5 variation, NM_000192.3:c.577G>T; p.(Gly193*), was discovered in a family with CHD and AF as well as BAV.The variation was absent in the 584 reference chromosomes as well as in suchpopulation databases as the 1000 Genomes Projectdatabase, the Genome AggregationDatabase, and the Single NucleotidePolymorphism database.