The two NLR groups had no significant differences with regard to age, gender, AFP, CA19-9, HbsAg, HCV Ab, liver cirrhosis, lymph node metastasis, perineural invasion, lymph-vascular invasion, histology grade, AJCC tumor stage or IHC cell predominance (Table 2). This evidence concerns the gene AFP and metastatic malignant neoplasm in the lymph nodes.