Therefore, using both a genetic and nutritional experimental model of NAFLD, the aims of this study have been to (a) determine the serum levels of trace elements (Ca2+, Cl, Fe, K, Na, Mg and Zn), and (b) evaluate a potential relationship between these trace elements, inflammatory markers (TNF-alpha, IL-1beta and IL-6) and uric acid. Here, IL6 is linked to metabolic dysfunction-associated steatotic liver disease.