Here we show major correlations between CD4+ T cells, neutrophils, DCs, M2 macrophages, TAMs, Tregs, exhausted T cells, and T helper cells with Fam20C, supporting the the important role of Fam20C in the immune contexture in BLCA, LGG, and STAD. The gene discussed is FAM20C; the disease is bladder transitional cell carcinoma.