Further, applying TCGA database of GEPIA to the analysis showed higher mRNA levels of Fam20C had an increased risk for shorter time for OS and DFS in most tumor types, including BLCA, CESC, and brain cancer (GBM and LGG), HNSC, and UVM (Figure 4C–E,H–L,N). The gene discussed is FAM20C; the disease is glioblastoma.