A dual cancer‐specific oncolytic adenovirus Ad‐Apoptin‐hTERTp‐E1A (Ad‐VT) with the Apoptin and hTERT promoter was constructed together with three control viruses Ad‐Apoptin (Ad‐VP3), Ad‐hTERTp‐E1A (Ad‐T) and Ad‐Mock.14 Here, UBN1 is linked to cancer.