In line with this finding, AOM/DSS model in mice, a powerful tool to investigate the mechanisms of colon carcinogenesis and development [53, 54], also proved the positive correlation among the expression of hTERT, SPT6, and SND1, implying again the potential regulation of hTERT by SPT6 and SND1 in CRC. This evidence concerns the gene SUPT6H and colorectal carcinoma.