SUPT6H and colorectal carcinoma: Of note, consistent with what we detect that hTERT expression was strictly controlled by SPT6, the ectopic overexpression of hTERT effectively reversed the above functional changes mediated by SPT6 silencing ex vivo, illustrating again the key role of hTERT in CRC tumorigenesis and development, and also implying the potential regulation of hTERT by SPT6 in CRC cells.