NPHS2 and Hypertension: The proband (II-1) displayed an NPHS2 polymorphism c.725C>T (p.Ala242Val) manifested as hematuria, persistent proteinuria (1500 mg/l), and normal renal function, while the father (I-1) of the proband had no history of hematuria, proteinuria, hypertension, or CKD.