PROM1 and cancer: It has been reported that in Indian triple negative breast cancers (TNBC) patients, the putative cancer stem cell marker CD133 or prominin-1 is correlated with the functional CSC signaling pathways including NOTCH-1/HES-1; Wnt/β-catenin; TGF-β III R/SMAD-7 and PTCH-1/Gli-1 (hedgehog) pathway activations (Bhaskara et al., 2019).