Besides, rs1801133 CT/CC genotype had an inverse association with the LSM2/LSM1 ratio (adjusted AMR = 0.80; 95%CI = 0.68–0.95; p = 0.009) and the cirrhosis progression (adjusted OR = 0.21; 95%CI = 0.06–0.74; p = 0.015) (Table 4). Here, LSM2 is linked to Cirrhosis.