Thereafter, to explore the effect of miR-320a on radioresistance of NSCLC via HIF1α, A549 and H23 cells were stimulated with mimic NC + oe-NC + 10 Gy, miR-320a mimic + oe-NC + 10 Gy, and miR-320a mimic + oe-HIF1α + 10 Gy. This evidence concerns the gene HIF1A and non-small cell lung carcinoma.