In addition, we examined the proliferation of trophoblasts treated with EZH2 inhibitor or transfected with EZH2 siRNA in the presence of AD-MSC-derived exosome or Baf A1, and found that the trophoblast proliferation had the same change curve as the autophagy activity (Figures 2D,E, 3D,E). Here, EZH2 is linked to Alzheimer disease.