In addition, low expression of YTHDC2 was correlated with worse OS in different cellular content (Basophils, B-cells, CD4+ memory cells, CD8+ T-cells, Eosinophils, Macrophages, Mesenchymal stem cells, Natural killer T-cells, Regulatory T-cells, Type 1 T-helper cells, Type 2 T-helper cells) of HNSCC patients (Table 1). This evidence concerns the gene CD4 and head and neck squamous cell carcinoma.