Since the EGFR signalling pathway is closely related to tumour cell growth, invasion, angiogenesis and metastasis (Hynes & Lane, 2005; Lee et al., 2017), we detected the expression of EGFR in NPC cells and NPC cell‐derived EVs, and found that EGFR was enriched in highly metastatic NPC cells and H‐EVs compared with low metastatic NPC cells and L‐EVs (Figure 2c). Here, EGFR is linked to nasopharyngeal carcinoma.