Intriguingly, in line with our findings, some previous lines of evidence have already shown that some of these hub genes like Cdk1 (cyclin-dependent kinase 1) (Wu et al., 2016) and Mki67 (Rahbar et al., 2018) were tightly involved in the pathogenesis of SLE or LN. The gene discussed is MKI67; the disease is lobular neoplasia.