FTO and obesity due to melanocortin 4 receptor deficiency: Serial GWAS studies on obesity-related traits in people of European descent have confirmed the important role of the FTO locus, and many other FTO SNPs in the intron 1 region have been reported, such as rs9930506, rs1421085, rs8050136, rs1121980, and so forth (Dina et al., 2007; Scuteri et al., 2007; Haupt et al., 2008; Cauchi et al., 2009).