In recent years, FTO SNPs have been firmly associated with increased body mass index (BMI) and higher risks of various types of cancers in people of multiple races, and the role of FTO SNPs in the development of obesity and cancer has been gradually revealed (Loos and Yeo, 2014; Hernández-Caballero and Sierra-Ramírez, 2015; Deng et al., 2018a; Chen and Du, 2019). The gene discussed is FTO; the disease is obesity due to melanocortin 4 receptor deficiency.