Recently, it was found that the CD157/BST1 gene polymorphisms are associated with some neurological diseases, including ASD (69, 70), which provoked to work with animals with a deletion of the CD157/BST1 gene and to evaluate the possibility of using CD157−/− mice as models of ASD or autistic-like behavior with a social deficit in the absence of motor dysfunctions (especially in childhood and early adolescent). Here, BST1 is linked to nervous system disorder.