Some examples include frontotemporal lobar degeneration associated with MAPT mutations (FTLD-MAPT), Pick's disease (PiD), corticobasal degeneration (CBD), progressive supranuclear palsy (PSP), globular glial tauopathy (GGT) and argyrophilic grain disease (AGD) (1, 2), with considerations of effects in different cell lineages included in Section cell lineages harboring abnormal forms of tau. This evidence concerns the gene MAPT and progressive supranuclear palsy.