ATM M1 polarisation is thought to promote insulin resistance and type 2 diabetes [23], while ATM M2 polarisation, induced by eosinophil-derived type 2 cytokines (for example, the interleukins Il4), increases brown adipose tissue (BAT) activation and white adipose tissue (WAT) browning [24, 25]. This evidence concerns the gene ATM and type 2 diabetes mellitus.