Its cell growth suppression activities against A549 (human lung carcinoma, G12S mutant), H1975 (human lung carcinoma, WT), MIA PaCa-2 (human pancreas carcinoma, G12C mutant), and Capan-1 (human pancreas carcinoma, G12V mutant) cells were significantly weaker than those against K-Ras(G12D)-expressing cells (Table 2). The gene discussed is KRAS; the disease is exocrine pancreatic carcinoma.