TNFRSF11A and neoplasm: Strikingly, when transplanted in T-cell-deficient Foxn1nu mice, no differences in latency to tumor onset were observed between RANK+/+ and RANK−/− tumor transplants, whereas the same tumors transplanted in syngeneic C57BL/6 mice corroborated previous results (Fig. 1d and Supplementary Fig. 2a)10.