PCSK9 and type 2 diabetes mellitus: The strengths of the current study include its large-scale, longitudinal follow-up of a high-risk population and extensive adjustment for key confounders and stratification of several potential risk factors that may have an effect on the PCSK9-type 2 diabetes relationship, including sex, waist circumference, LDL-C, HOMA-IR, and menopausal status.