PCSK9 and type 2 diabetes mellitus: Above the inflection point at 375 ng/mL, the risk of incident type 2 diabetes increased with increasing PCSK9 levels in female subjects (1.90 [1.06-3.40] at 400 ng/mL, 2.14 [1.21-3.78] at 450 ng/mL, 2.31 [1.31-4.10] at 500 ng/mL, and 2.50 [1.29-4.86] at 550 ng/mL) (Fig. 4).