Compared with the low PCSK9 group, the high PCSK9 group were older and had high SBP, waist circumference, FPG, insulin, HOMA-IR, LDL-C, TC, TG, ALT, AST, GGT, and CRP, as well as a higher proportion of smokers and hypertension (Additional file 1: Table S3). The gene discussed is PCSK9; the disease is hypertensive disorder.