IGHE and chronic idiopathic urticaria: The present section will focus on some approaches targeting this axis, most of them being also developed in other autoimmune or atopic conditions where IgE and FcεRI-bearing cells are known to be essential in the pathogenesis, like chronic spontaneous urticaria (CSU), bullous pemphigoid, allergic asthma or atopic dermatitis [19,62,63,64,65].