CD81 and glioblastoma: This is quite relevant to the field of EGFR research, as both EGFR and its glioblastoma mutant EGFRvIII can be found on Flotillin1+ sEVs extracted from the blood of glioblastoma and ovarian cancer patients [23,119], as well as on CD9+/CD81+ sEVs as mentioned above.