EGFR and glioblastoma: The role of EGFR in miRNA maturation [180] through its interactions with AGO2 [181] opens another interesting avenue of investigation, as EGFR or EGFRvIII amplification in glioblastoma is associated with higher grade [97], which in turn is associated with a specific pattern of sEV-packaged miRNAs regulating pro-tumoural functions in the microenvironment [182].