During cancer development, several proangiogenic cytokines are released by tumor cells, such as vascular endothelial growth factor A (VEGFA), fibroblast growth factor (FGF) and hypoxia-inducible factor-1 (HIF-1), which contributes to the sprout and formation of neovasculature in the tumor microenvironment (TME) [9]. Here, VEGFA is linked to neoplasm.