pCR was achieved in 51 (31.7%) patients. In patients with TNBC treated with neoadjuvant platinum-based therapy, iTIL and sTIL densities were not significantly associated with BRCA1/2-mutated tumor status (p = 0.312 and p = 0.391). In multivariate analyses, sTIL density (OR 1.23, 95% CI 0.94–1.61, p = 0.139) was not associated with pCR, but was associated with RCB 0/I status (OR 1.62, 95% CI 1.20–2.28, p = 0.001). This evidence concerns the gene BRCA1 and neoplasm.