In this work we tested an extract from DF in therapeutically relevant concentration range in terms of cell viability, proliferation, regulation of VEGF secretion and gene expression of VEGF-A, FLT-1/VEGFR1 (fms related receptor tyrosine kinase 1/VEGF receptor 1) and KDR/VEGFR2 (kinase insert domain receptor/VEGF receptor 2) after short- and mid-term time period stimulation of the tumor cell line OMM-1 and the human primary glioblastoma cultures 116-14 and 118-14. Here, KDR is linked to neoplasm.