The four molecules IL-1Ra, IL-7, MIP-1a, and MIP-1b were confirmed to have a significant (p < 0.0001) differential expression in melanoma (Figure 9), and their combined analysis with the PCA methodology (a different methodology compared to SVM) was found to effectively discriminate the controls from the melanoma samples (Figure 10). The gene discussed is IL6R; the disease is melanoma.