Figure S2 illustrates the mitochondrial part of the oxidative phosphorylation landscapes. The analysis showed again that PTA and CWM have similar landscapes, while PTB was found to be closer to NOR. Interestingly, none of the genes from the most relevant five mitochondrial gene pairs in PTA (ATP6, COX2, COX3, CYTB), PTB (COX1, COX2, COX3, CYTB, ND2), and CWM (COX1, COX3, CYTB, ND4L) were regulated by cancer in their respective regions. The gene discussed is PTGS2; the disease is cancer.