A total of 15 transcription factors were shared between a nuts-supplemented diet and dementia (ELK1, EGR1, PPARG, YY1, STAT1, CREB1, GATA2, GATA3, CEBPB, RELA, STAT3, SREBF1, E2F4, JUN, and RUNX1) (Figure 7e). This evidence concerns the gene E2F4 and dementia.