F10 and atherosclerosis: Coagulation factors, not only participate to the activation of the coagulation cascade but also impact vascular function; this is the case for factor X (FXa), one of the main components in the coagulation process [3], which, through the activation of protease-activated receptors (PAR) [4], affects, vasomotor responses, inflammation, endothelial function, vascular proliferation, cellular hypertrophy, atherosclerosis, and thrombosis [5,6].