Therefore, lung adenocarcinoma patients with higher GBP1 expression presented with poor survival23; (b) secondly, GBP1 might promote the invasiveness of lung adenocarcinoma via promoting cell motility, increasing the recurrence risk and contributing to undesirable survival profiles in patients with lung adenocarcinoma12; (c) thirdly, considering the correlation of GBP1 with increased chemotherapy resistance, patients with GBP1 high expression might present reduced treatment response, and further long‐term worse survival profiles.11, 22. This evidence concerns the gene GBP1 and lung adenocarcinoma.