GBP1 and neoplasm: To further detect the correlation of GBP1 expression with DFS in lung adenocarcinoma patients, we conducted univariate Cox's proportional hazard regression and found that GBP1 high expression (HR = 1.828, P < .001), worse pathological differentiation (HR = 1.277, P = .033), tumor size >5 cm (HR = 1.458, P = .014), LYN metastasis positive (HR = 2.805, P < .001), higher TNM stage (HR = 1.477, P < .001), and preoperative CEA abnormal (>5 ng/mL) (HR = 1.526, P = .007) were correlated with worse DFS (Table 4).