Additionally, the knocking down of NF‐κB suppressed the EGFRvIII overexpressing glioma cell bearing‐tumour growth in vivo with the inhibition of angiogenesis, indicating the crucial role of NF‐κB in EGFRvIII enhancing the carcinogenic capacity126 (Table 1). This evidence concerns the gene NFKB1 and central nervous system cancer.