MiR‐129‐5p overexpression obviously reduced the MMP‐2 and MMP‐9 protein levels and the luciferase activities of NF‐κB, indicating that miR‐129‐5p blocked the NF‐κB pathways to suppress glioma angiogenesis and growth (Figure 4). The gene discussed is MMP9; the disease is central nervous system cancer.