As depicted in Figure 3(c), the CNV rates of five obesity-related genes in cancer tissues were >0.05 (i.e., KCTD15 in ESCA (0.06), OSC (0.08), and UCS (0.19); POMC in UCS (0.06); TMEM18 in UCS (0.06)). This evidence concerns the gene TMEM18 and obesity due to melanocortin 4 receptor deficiency.