In addition, gender and expression levels of other seven obesity-related genes (GPR120, LEP, MC4R, TMEM18, PCSK1, NEGR1, and FTO) could markedly affect survival probability of patients with 11 types of cancer (ACC, KIRC, UVM, ESCA, SKCM, KIRP, BLCA, STAD, CHOL, COAD, and LGG). The gene discussed is TMEM18; the disease is obesity due to melanocortin 4 receptor deficiency.