However, race and expression levels of the other eight obesity-related genes (SH2B1, GNPDA2, LEPR, TMEM18, KCTD15, GPR120, MC4R, and FTO) noticeably affected the survival probability of patients with 15 types of cancer (SKCM, KIRP, LUSC, KICH, HNSC, KIRC, DLBC, LIHC, THCA, THYM, BLCA, ESCA, PRAD, GBM, and BRCA), especially SKCM and KICH. The gene discussed is TMEM18; the disease is obesity due to melanocortin 4 receptor deficiency.