CHL1 and nasopharyngeal carcinoma: They include, for example, how microRNA-29 targets FGF2 and inhibits the proliferation, migration, and invasion of nasopharyngeal carcinoma cells via the PI3K/AKT signaling pathway; CHL1 suppresses tumor growth and metastasis in nasopharyngeal carcinoma by repressing the PI3K/AKT signaling pathway via interaction with Integrin β1 and Merlin [33]; and microRNA-29 targets FGF2 and inhibits the proliferation, migration, and invasion of nasopharyngeal carcinoma cells via the PI3K/AKT signaling pathway [34].