For instance, unlike conditioned medium from human adipose MSCs, eicosapentanoic acid-treated adipose MSCs reduce mRNA levels of the tumor-associated genes FASN, STAT3, and cIAP-2 in MDA-MB-231 and MCF-7 breast cancer cell lines, with marked decreases in their glycolysis, inflammation, and motility in vivo106. This evidence concerns the gene STAT3 and neoplasm.