After adjustment for age, incidence of diabetes, dialysis vintage, ALB, and median FGF23 level, the median sKlotho level was still strongly associated with combined adverse outcomes [1.818 (1.092–3.026), p = 0.021] including CV morbidity [1.942 (1.030–3.661), p = 0.040)] and all-cause mortality [2.073 (1.023–4.203), p = 0.043] in the adjusted models (Table 4). The gene discussed is FGF23; the disease is diabetes mellitus.