Potential risk factors for DFS by the univariable Cox analysis including HGB (P=0.004), Ccr (P=0.001), symptom (P=0.001), surgery (P=0.002), tumour size (P < 0.001), tumour type (P < 0.001), TNM stage (P < 0.001), Fuhrman grade (P < 0.001), RLR (P < 0.001), and AFR (P < 0.001) were enrolled into the multivariate Cox analysis (Table 3). This evidence concerns the gene CYGB and neoplasm.